Infectious lesions of the external nose: causes, manifestations, diagnosis and treatment

Infectious lesions of the external nose include diseases of the skin of the external nose, the etiological factor of which is a bacterial infection and the presence of favorable conditions. The affected area includes the skin, hair follicles, subcutaneous fatty tissue, while the mucous membrane remains intact.

Classification

Nasal furuncle:

• Infiltration stage;
• Abscission stage.

Other diseases:

• Sycosis of the nasal vestibule;
• Nasal eczema;
• Rhinitis nasal inflammation.

Etiology

The leading role in the occurrence of the above diseases is attributed to bacterial pathogens: staphylococci (S. aureus, S. epidermidis, S. saprophyticus) and streptococci(β-hemolytic group A). The infection develops in the presence of a number of factors, such as damage to the skin (presence of abrasions, cracks, maceration) and a decrease in the general reactivity of the body. With metabolic disorders (concomitant diabetes mellitus), immune insufficiency is noted extremely unfavorable course.

Nasal eczema develops with a combination of several triggering factors: maceration of the skin by pathologic secretions (presence of chronic infection of the nasal cavity or paranasal sinuses), contact allergy and concomitant extraorganic pathology (diabetes mellitus, atopic dermatitis, food allergy, thyroid disease).

Anatomy

Nasal furuncle is a purulent-necrotic lesion of the hair follicle, sebaceous gland and surrounding tissues (subcutaneous fatty tissue, skin). This process involves the tip, wings or vestibule of the nose, the area of the upper lip, but it should be remembered that the process is always limited to the skin and never passes to the mucous membrane of the nasal cavity (due to the absence of hair follicles in it).

If several hair follicles located in the same area are affected, it is called a carbuncle. A furuncle is characterized by the stages of the process: the stage of infiltration, the stage of abscessation and the stage of healing. In the first stage there is local infiltration, thickening and hyperemia of the skin at the site of inflammation, centrally located hair shaft, a few days later the process passes into the second stage and purulent content is formed with tissue melting and fluctuation, which in rare cases can open independently.

Upon recovery, the affected area is filled with connective tissue. In severe course of the process can develop formidable complications, such as thrombosis of the cavernous sinus, brain abscess and sepsis, which, in turn, can lead to death. The pathogenesis is based on infection along the venous outflow from the nasal antrum through the angular and ocular veins into the cavernous sinus, where a thrombus subsequently forms.

Nasal sycosis (folliculitis) is characterized by lesions only in the hair follicles, most often in a group in the area of the nasal vestibule or on the upper lip; the underlying tissues remain intact. Pustules with purulent content are formed on hyperemic and infiltrated skin in the hair area, which open on 2-3 days and are subsequently covered with crusts.

Nasal eczema is a lesion of the epidermis and is characterized by a staged process. On the affected hyperemic skin papules and vesicles are formed, which after a few days open and serous content is released. After 1-2 days, the affected area is covered with crusts, scales, which are then independently rejected, in some cases leaving a zone of depigmentation.

Rhinitis nasalis (Latin erysipelas) is an infectious inflammation of the skin and subcutaneous fatty tissue with involvement of nearby lymphatic vessels and lymph nodes. The skin becomes sharply hyperemic, edematous, hot, the borders of the lesion are clearly delineated, in some cases, serous or serous-hemorrhagic blisters are formed on the surface of the skin. Adjacent lymph nodes are enlarged.

Clinicalclinical manifestations

Nasal furuncle in the infiltration stage is characterized by pronounced pain at the site of inflammation (after 1-2 days, the pain becomes throbbing, increases), the skin is hyperemic, the surrounding tissues are edematous, there may be signs of general intoxication, such as weakness, headache, fever to febrile values, enlargement of regional lymph nodes. After 2-3 days, when the process passes to the stage of abscission, the patient notes a significant relief of the general condition, pain decreases, as noted above, the purulent rod can be opened and rejected independently, in this case there is abundant purulent or purulent-hemorrhagic discharge from the lesion area, manifestations of general intoxication pass. In recovery, a small scar is formed.

When complications occur, such as cavernous sinus thrombosis, the clinic may vary, the symptoms of general intoxication always increase, patients note a pronounced throbbing headache and eye pain, nausea, vomiting, decreased vision, seizures or loss of consciousness may occur. Local manifestations extend to the ocular region, accompanied by exophthalmos, chemosis, ptosis on the affected side.

Sycosis of the nasal vestibule is characterized by itching and burning at the lesion site, there may be skin tension with slight soreness. The skin is dimly hyperemic, sparingly defined pitting wetting. Then crusts are formed around the hair shafts, which are often combed, which contributes to the chronicization of the process with periods of exacerbation and remission. In rare cases, general intoxication of the body increases, temperature rises to 38-38.5°C, weakness and enlarged regional lymph nodes.

Nasal eczema is more often characterized by a chronic course, in the period of exacerbation there is severe itching and marked soreness in the affected area, at the time of opening vesicles, the skin becomes moist and then covered with itchy crusts. The skin thickens and the skin pattern becomes more pronounced. Itching bothers patients so much that in some cases it leads to insomnia.

Nasal swelling is manifested by redness and swelling of the skin, the affected area has clear boundaries (demarcation line), when touching – sharp soreness, the skin is hot to the touch, in some cases presented in the form of a butterfly, with lesions of the skin of the nose and cheek area on 2 sides. If there are serous or serous-hemorrhagic blisters, they self-open and a wet surface is formed, which is then covered with a crust. Acute intoxication with fever up to 39-40°C, chills, marked weakness, headache, and vomiting may be characteristic of rheumatoid inflammation. On 7-10 days with adequate treatment the process is eliminated. In some cases, inflammation may be complicated by cavernous sinus thrombosis and sepsis.

Diagnosis

Clinical examination of the affected area is used to make a diagnosis. Evaluation of laboratory indicators, such as a general blood count (changes in the number of leukocytes, leukocyte formula), biochemical blood count (CRP, glucose level) is performed. Also necessarily performed bacteriologic seeding of wound discharge and tissues to determine the causative agent and clarify sensitivity to antibiotics. If complications occur, CT and MRI are performed, additionally, blood culture for sterility and lumbar puncture may be prescribed. To clarify the cause of nasal eczema, allergy tests are performed in some cases.

Find more science-based content on our social media channels

Subscribe and don’t miss out on the latest resources

Treatment Infectious lesions of the external nose

With a mild course of diseases (furuncle and sycosis), local treatment prevails. Ointments with NSAIDs and antibiotics are prescribed, antiseptic treatment of foci for 5-7 days until resolution of symptoms. A good effect is noted with physical therapy, especially UV radiation.

In case of progression of the process (transition to the abscessed stage), surgical treatment is indicated – opening and sanation of the purulent focus in the place of the largest swelling with the installation of drainage and aseptic dressing. Subsequently, regular dressings are performed until complete healing.

In some cases, at the discretion of the doctor (in the absence of effect from local treatment, severe general intoxication, prolonged course) prescribe antibacterial drugs orally for a course of 5-7 days, taking into account sensitivity.

In the recovery stage, wound-healing and regenerating ointments are used.

In the presence of complications, emergency hospitalization is indicated.

In the treatment of eczema, the basis is also local treatment, in the acute period ointments with glucocorticosteroids are used, in case of infection of the skin, combined preparations with antibiotics are added. The skin is regularly treated with antiseptic solutions. To reduce itching and combing of the skin, antihistamines are prescribed orally, in some cases sedatives are prescribed. During the healing period (formation of crusts and scales) apply healing ointments and moisturizing lotions. During remission, the skin should be moisturized abundantly and regularly to prevent the development of exacerbations. It should be remembered that eczema is a polyetiologic disease and for the successful cure of skin manifestations it is necessary to treat concomitant chronic diseases.

For the treatment of swelling, antibiotic therapy is necessarily prescribed (drugs of choice – penicillin series, correction according to the results of bacteriological culture), orally or parenterally, depending on the severity of the condition, since the disease is prone to recurrence and has a number of formidable complications. Local antiseptic treatment of the affected area, physiotherapy with UV radiation is performed.