{"id":8429,"date":"2026-10-22T16:36:10","date_gmt":"2026-10-22T13:36:10","guid":{"rendered":"https:\/\/wiki.voka.io\/glossary\/mialgia\/"},"modified":"2026-10-22T16:36:14","modified_gmt":"2026-10-22T13:36:14","slug":"mialgia","status":"publish","type":"glossary_item","link":"https:\/\/wiki.voka.io\/pt\/glossario\/mialgia\/","title":{"rendered":"Mialgia"},"content":{"rendered":"\n

Mialgia (do grego myos<\/em> \u2014 m\u00fasculo e algos<\/em> \u2014 dor) \u2014 \u00e9 uma s\u00edndrome dolorosa na musculatura estriada (esquel\u00e9tica). Na infectologia, esse sintoma \u00e9 um dos marcadores b\u00e1sicos da resposta inflamat\u00f3ria sist\u00eamica ou um sinal de acometimento parasit\u00e1rio direto do tecido muscular.<\/p>\n\n

Etiologia e fisiopatologia<\/h2>\n\n

O mecanismo de desenvolvimento da mialgia divide-se em dois tipos:<\/p>\n\n

    \n
  • t\u00f3xico-infeccioso<\/strong> \u2014 esse tipo de mialgia (caracter\u00edstico da influenza, da infec\u00e7\u00e3o por coronav\u00edrus e da dengue) ocorre sem a presen\u00e7a f\u00edsica do v\u00edrus nos m\u00fasculos. Ela \u00e9 causada pela libera\u00e7\u00e3o maci\u00e7a de citocinas pr\u00f3-inflamat\u00f3rias no sangue (especialmente do fator de necrose tumoral e da interleucina-6). Essas mol\u00e9culas aumentam acentuadamente a sensibilidade dos nociceptores (receptores de dor) nas fibras musculares, causando uma sensa\u00e7\u00e3o de dor difusa em todo o corpo;<\/li>\n\n\n\n
  • invasivo<\/strong> \u2014 apresenta uma natureza completamente distinta. Esse tipo de mialgia \u00e9 t\u00edpico das helmint\u00edases, particularmente da triquinelose. Nesse caso, as larvas do parasita s\u00e3o transportadas pela corrente sangu\u00ednea e penetram fisicamente no interior da fibra muscular (mais frequentemente nos m\u00fasculos gastrocn\u00eamios, mastigat\u00f3rios e deltoides). A larva enrola-se em espiral e \u00e9 recoberta por uma c\u00e1psula densa (encapsulamento). Isso causa um processo inflamat\u00f3rio local (miosite), edema tecidual e dor aguda e extenuante ao menor movimento.<\/li>\n<\/ul>\n\n

    Import\u00e2ncia cl\u00ednica<\/h2>\n\n

    A natureza da mialgia auxilia o m\u00e9dico no diagn\u00f3stico diferencial:<\/p>\n\n

      \n
    • dor difusa (sensa\u00e7\u00e3o de dor surda ou desconforto nos m\u00fasculos e nas articula\u00e7\u00f5es de todo o corpo)<\/strong> \u2014 em associa\u00e7\u00e3o com febre alta e manifesta\u00e7\u00f5es catarrais, indica uma infec\u00e7\u00e3o viral respirat\u00f3ria aguda (IVRA). Nesse caso, o tratamento consiste na administra\u00e7\u00e3o de anti-inflamat\u00f3rios n\u00e3o esteroides para bloquear a s\u00edntese de prostaglandinas;<\/li>\n\n\n\n
    • dor muscular localizada e progressiva<\/strong> \u2014 acompanhada de edema facial, febre e eosinofilia acentuada, \u00e9 um sinal patognom\u00f4nico de triquinelose. Nesse caso, \u00e9 necess\u00e1ria a administra\u00e7\u00e3o imediata de medicamentos anti-helm\u00ednticos, \u00e0s vezes (em casos graves) em associa\u00e7\u00e3o com glicocorticosteroides sist\u00eamicos.<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"

      Mialgia (do grego myos<\/em> \u2014 m\u00fasculo e algos<\/em> \u2014 dor) \u2014 \u00e9 uma s\u00edndrome dolorosa na musculatura estriada (esquel\u00e9tica). Na infectologia, esse sintoma \u00e9 um dos marcadores b\u00e1sicos da resposta inflamat\u00f3ria sist\u00eamica ou um sinal de acometimento parasit\u00e1rio direto do tecido muscular.<\/p>\n","protected":false},"featured_media":0,"template":"","class_list":["post-8429","glossary_item","type-glossary_item","status-publish","hentry"],"acf":[],"yoast_head":"\nMialgia: defini\u00e7\u00e3o m\u00e9dica e vis\u00e3o geral | Voka Wiki<\/title>\n<meta name=\"description\" content=\"Mialgia (do grego myos \u2014 m\u00fasculo e algos \u2014 dor) \u2014 \u00e9 uma s\u00edndrome dolorosa na musculatura estriada (esquel\u00e9tica). Na infectologia, esse sintoma \u00e9 um dos marcadores b\u00e1sicos da resposta inflamat\u00f3ria sist\u00eamica ou um sinal de acometimento parasit\u00e1rio direto do tecido muscular.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/wiki.voka.io\/pt\/glossario\/mialgia\/\" \/>\n<meta property=\"og:locale\" content=\"pt_PT\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Mialgia\" \/>\n<meta property=\"og:description\" content=\"Mialgia (do grego myos \u2014 m\u00fasculo e algos \u2014 dor) \u2014 \u00e9 uma s\u00edndrome dolorosa na musculatura estriada (esquel\u00e9tica). 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