{"id":8401,"date":"2026-10-22T16:37:30","date_gmt":"2026-10-22T13:37:30","guid":{"rendered":"https:\/\/wiki.voka.io\/glossary\/imunoglobulina-g\/"},"modified":"2026-10-22T16:37:33","modified_gmt":"2026-10-22T13:37:33","slug":"imunoglobulina-g","status":"publish","type":"glossary_item","link":"https:\/\/wiki.voka.io\/pt\/glossario\/imunoglobulina-g\/","title":{"rendered":"Imunoglobulina G"},"content":{"rendered":"\n

Imunoglobulina G, ou IgG (do lat. immunitas<\/em> \u2014 libera\u00e7\u00e3o, liberta\u00e7\u00e3o de algo e globulus<\/em> \u2014 esfera, gota; G \u2014 a primeira letra do grego gamma<\/em> \u2014 nome do tipo de cadeia proteica) \u2014 \u00e9 a principal e mais numerosa classe de anticorpos protetores no soro sangu\u00edneo humano (representa at\u00e9 75\u201380% de todas as imunoglobulinas).<\/p>\n\n

\u00c9 a principal arma da imunidade adquirida, proporcionando prote\u00e7\u00e3o duradoura e confi\u00e1vel ao organismo contra a reinfec\u00e7\u00e3o.<\/p>\n\n

Etiologia e fisiopatologia<\/h2>\n\n

As mol\u00e9culas de IgG apresentam v\u00e1rias propriedades espec\u00edficas:<\/p>\n\n

    \n
  • s\u00edntese pelos linf\u00f3citos B<\/strong> \u2014 ocorre nas fases tardias da infec\u00e7\u00e3o prim\u00e1ria (geralmente 2\u20133 semanas ap\u00f3s a infec\u00e7\u00e3o) ou imediatamente ap\u00f3s novo contato com um pat\u00f3geno j\u00e1 conhecido;<\/li>\n\n\n\n
  • forma cl\u00e1ssica em Y e tamanho pequeno<\/strong> \u2014 permitem que a IgG passe facilmente da corrente sangu\u00ednea para os tecidos para destruir v\u00edrus e bact\u00e9rias;<\/li>\n\n\n\n
  • passagem pela barreira placent\u00e1ria<\/strong> \u2014 uma caracter\u00edstica \u00fanica. Na superf\u00edcie da placenta, existem receptores neonatais especiais de transporte (FcRn), que capturam as IgG maternas e as transportam para a corrente sangu\u00ednea fetal. Nenhuma outra classe de anticorpos \u00e9 capaz disso.<\/li>\n<\/ul>\n\n

    Import\u00e2ncia cl\u00ednica<\/h2>\n\n

    A detec\u00e7\u00e3o de imunoglobulina G no sangue do paciente indica, na maioria dos casos, uma doen\u00e7a pregressa ou uma vacina\u00e7\u00e3o realizada com sucesso. A presen\u00e7a de IgG indica a exist\u00eancia de imunidade.<\/p>\n\n

    Para o rec\u00e9m-nascido, as IgG maternas s\u00e3o vitais. Elas conferem imunidade passiva, protegendo o lactente contra a maioria das infec\u00e7\u00f5es perigosas (por exemplo, sarampo, influenza e coqueluche) nos primeiros meses de vida, enquanto ainda n\u00e3o pode ser vacinado de acordo com a idade e n\u00e3o come\u00e7ou a produzir seus pr\u00f3prios anticorpos.<\/p>\n\n

    <\/p>\n","protected":false},"excerpt":{"rendered":"

    Imunoglobulina G, ou IgG (do lat. immunitas<\/em> \u2014 libera\u00e7\u00e3o, liberta\u00e7\u00e3o de algo e globulus<\/em> \u2014 esfera, gota; G \u2014 a primeira letra do grego gamma<\/em> \u2014 nome do tipo de cadeia proteica) \u2014 \u00e9 a principal e mais numerosa classe de anticorpos protetores no soro sangu\u00edneo humano (representa at\u00e9 75\u201380% de todas as imunoglobulinas). <\/p>\n","protected":false},"featured_media":0,"template":"","class_list":["post-8401","glossary_item","type-glossary_item","status-publish","hentry"],"acf":[],"yoast_head":"\nImunoglobulina G: defini\u00e7\u00e3o m\u00e9dica e vis\u00e3o geral | Voka Wiki<\/title>\n<meta name=\"description\" content=\"Imunoglobulina G, ou IgG (do lat. immunitas \u2014 libera\u00e7\u00e3o, liberta\u00e7\u00e3o de algo e globulus \u2014 esfera, gota; G \u2014 a primeira letra do grego gamma \u2014 nome do tipo de cadeia proteica) \u2014 \u00e9 a principal e mais numerosa classe de anticorpos protetores no soro sangu\u00edneo humano (representa at\u00e9 75\u201380% de todas as imunoglobulinas).\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/wiki.voka.io\/pt\/glossario\/imunoglobulina-g\/\" \/>\n<meta property=\"og:locale\" content=\"pt_PT\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Imunoglobulina G\" \/>\n<meta property=\"og:description\" content=\"Imunoglobulina G, ou IgG (do lat. immunitas \u2014 libera\u00e7\u00e3o, liberta\u00e7\u00e3o de algo e globulus \u2014 esfera, gota; 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