{"id":8359,"date":"2026-09-17T15:54:28","date_gmt":"2026-09-17T12:54:28","guid":{"rendered":"https:\/\/wiki.voka.io\/glossary\/revacinacao\/"},"modified":"2026-10-22T16:39:08","modified_gmt":"2026-10-22T13:39:08","slug":"revacinacao","status":"publish","type":"glossary_item","link":"https:\/\/wiki.voka.io\/pt\/glossario\/revacinacao\/","title":{"rendered":"Revacina\u00e7\u00e3o"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">Revacina\u00e7\u00e3o (do lat. <em>re-<\/em> \u2014 renova\u00e7\u00e3o, repeti\u00e7\u00e3o e <em>vaccinus<\/em> \u2014 bovino) \u00e9 a administra\u00e7\u00e3o repetida de um ant\u00edgeno vacinal a uma pessoa que j\u00e1 concluiu anteriormente o esquema completo de imuniza\u00e7\u00e3o prim\u00e1ria.<\/p>\n\n<p class=\"wp-block-paragraph\">O objetivo desse procedimento \u00e9 restaurar ou refor\u00e7ar a imunidade adquirida, que tende a diminuir naturalmente ao longo do tempo.<\/p>\n\n<h2 id=\"h-&#x44D;&#x442;&#x438;&#x43E;&#x43B;&#x43E;&#x433;&#x438;&#x44F;-&#x438;-&#x43F;&#x430;&#x442;&#x43E;&#x444;&#x438;&#x437;&#x438;&#x43E;&#x43B;&#x43E;&#x433;&#x438;&#x44F;\" class=\"wp-block-heading\">Etiologia e fisiopatologia<\/h2>\n\n<p class=\"wp-block-paragraph\">Ap\u00f3s uma vacina\u00e7\u00e3o prim\u00e1ria bem-sucedida, forma-se no organismo um conjunto de c\u00e9lulas de mem\u00f3ria imunol\u00f3gica (linf\u00f3citos T e B).<\/p>\n\n<p class=\"wp-block-paragraph\">No entanto, se o sistema imunol\u00f3gico n\u00e3o entrar em contato durante anos com um v\u00edrus selvagem real ou uma bact\u00e9ria real, a quantidade de anticorpos protetores circulantes e de c\u00e9lulas espec\u00edficas diminui gradualmente at\u00e9 um n\u00edvel criticamente baixo (fen\u00f4meno de decl\u00ednio da imunidade).<\/p>\n\n<p class=\"wp-block-paragraph\">A revacina\u00e7\u00e3o funciona como um \u00ablembrete\u00bb. Com a administra\u00e7\u00e3o repetida do ant\u00edgeno, ocorre a ativa\u00e7\u00e3o imediata das c\u00e9lulas de mem\u00f3ria quiescentes.<\/p>\n\n<p class=\"wp-block-paragraph\">Desenvolve-se uma resposta imune secund\u00e1ria: ocorre a r\u00e1pida s\u00edntese de anticorpos da classe IgG.<\/p>\n\n<h2 id=\"h-&#x43A;&#x43B;&#x438;&#x43D;&#x438;&#x447;&#x435;&#x441;&#x43A;&#x43E;&#x435;-&#x437;&#x43D;&#x430;&#x447;&#x435;&#x43D;&#x438;&#x435;\" class=\"wp-block-heading\">Import\u00e2ncia cl\u00ednica<\/h2>\n\n<p class=\"wp-block-paragraph\">O conceito de revacina\u00e7\u00e3o constitui a base do Calend\u00e1rio Nacional de Vacina\u00e7\u00e3o de crian\u00e7as e adultos em muitos pa\u00edses. Na pr\u00e1tica m\u00e9dica, distinguem-se v\u00e1rias indica\u00e7\u00f5es principais para o uso de doses de refor\u00e7o:<\/p>\n\n<ul class=\"wp-block-list\">\n<li><strong>contra difteria e t\u00e9tano<\/strong> \u2014 a imunidade n\u00e3o \u00e9 vital\u00edcia, portanto, os adultos necessitam de revacina\u00e7\u00e3o regular a cada 10 anos;<\/li>\n\n\n\n<li><strong>contra algumas infec\u00e7\u00f5es (por exemplo, coqueluche)<\/strong> \u2014 a revacina\u00e7\u00e3o \u00e9 importante na adolesc\u00eancia e na idade adulta, pois o efeito da vacina\u00e7\u00e3o realizada na inf\u00e2ncia desaparece ap\u00f3s 3\u20135 anos;<\/li>\n\n\n\n<li><strong>para prote\u00e7\u00e3o contra v\u00edrus propensos a muta\u00e7\u00f5es r\u00e1pidas (por exemplo, o coronav\u00edrus)<\/strong> \u2014 as doses de refor\u00e7o s\u00e3o administradas para manter a prote\u00e7\u00e3o. Nesse caso, a revacina\u00e7\u00e3o n\u00e3o apenas aumenta o t\u00edtulo total de anticorpos, mas tamb\u00e9m \u00abatualiza\u00bb a base de dados imunol\u00f3gica, apresentando ao organismo novas cepas do agente patog\u00eanico.<\/li>\n<\/ul>\n\n<p class=\"wp-block-paragraph\"><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Revacina\u00e7\u00e3o (do lat. <em>re-<\/em> \u2014 renova\u00e7\u00e3o, repeti\u00e7\u00e3o e <em>vaccinus<\/em> \u2014 bovino) \u00e9 a administra\u00e7\u00e3o repetida de um ant\u00edgeno vacinal a uma pessoa que j\u00e1 concluiu anteriormente o esquema completo de imuniza\u00e7\u00e3o prim\u00e1ria.<\/p>\n","protected":false},"featured_media":0,"template":"","class_list":["post-8359","glossary_item","type-glossary_item","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v25.0 (Yoast SEO v27.8) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Revacina\u00e7\u00e3o: 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