{"id":8362,"date":"2026-09-17T15:54:28","date_gmt":"2026-09-17T12:54:28","guid":{"rendered":"https:\/\/wiki.voka.io\/glossary\/revaccination\/"},"modified":"2026-10-22T16:39:11","modified_gmt":"2026-10-22T13:39:11","slug":"revaccination","status":"publish","type":"glossary_item","link":"https:\/\/wiki.voka.io\/fr\/glossaire\/revaccination\/","title":{"rendered":"Revaccination"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">La revaccination (du latin <em>re-<\/em> \u2014 renouvellement, r\u00e9p\u00e9tition et <em>vaccinus<\/em> \u2014 bovin) est l\u2019administration r\u00e9p\u00e9t\u00e9e d\u2019un antig\u00e8ne vaccinal \u00e0 une personne ayant d\u00e9j\u00e0 suivi un sch\u00e9ma complet de primovaccination.<\/p>\n\n<p class=\"wp-block-paragraph\">Cette proc\u00e9dure vise \u00e0 restaurer ou \u00e0 renforcer l\u2019immunit\u00e9 acquise, qui tend \u00e0 d\u00e9cliner naturellement au fil du temps.<\/p>\n\n<h2 id=\"h-&#x44D;&#x442;&#x438;&#x43E;&#x43B;&#x43E;&#x433;&#x438;&#x44F;-&#x438;-&#x43F;&#x430;&#x442;&#x43E;&#x444;&#x438;&#x437;&#x438;&#x43E;&#x43B;&#x43E;&#x433;&#x438;&#x44F;\" class=\"wp-block-heading\">\u00c9tiologie et physiopathologie<\/h2>\n\n<p class=\"wp-block-paragraph\">Apr\u00e8s une primovaccination r\u00e9ussie, un contingent de cellules de la m\u00e9moire immunologique (lymphocytes T et B) se constitue dans l\u2019organisme.<\/p>\n\n<p class=\"wp-block-paragraph\">Cependant, si le syst\u00e8me immunitaire n\u2019est pas confront\u00e9 pendant des ann\u00e9es \u00e0 un v\u00e9ritable virus sauvage ou \u00e0 une bact\u00e9rie, le nombre d\u2019anticorps protecteurs circulants et de cellules sp\u00e9cifiques diminue progressivement jusqu\u2019\u00e0 atteindre un niveau extr\u00eamement faible (ph\u00e9nom\u00e8ne de d\u00e9clin de l\u2019immunit\u00e9).<\/p>\n\n<p class=\"wp-block-paragraph\">La revaccination agit comme un \u00ab rappel \u00bb. La r\u00e9administration de l\u2019antig\u00e8ne entra\u00eene l\u2019activation imm\u00e9diate des cellules m\u00e9moire quiescentes.<\/p>\n\n<p class=\"wp-block-paragraph\">Une r\u00e9ponse immunitaire secondaire se d\u00e9veloppe : une synth\u00e8se rapide d\u2019anticorps de classe IgG se produit.<\/p>\n\n<h2 id=\"h-&#x43A;&#x43B;&#x438;&#x43D;&#x438;&#x447;&#x435;&#x441;&#x43A;&#x43E;&#x435;-&#x437;&#x43D;&#x430;&#x447;&#x435;&#x43D;&#x438;&#x435;\" class=\"wp-block-heading\">Importance clinique<\/h2>\n\n<p class=\"wp-block-paragraph\">Le concept de revaccination constitue le fondement du calendrier national de vaccination des enfants et des adultes dans de nombreux pays. En pratique m\u00e9dicale, plusieurs indications principales des doses de rappel sont distingu\u00e9es :<\/p>\n\n<ul class=\"wp-block-list\">\n<li><strong>contre la dipht\u00e9rie et le t\u00e9tanos<\/strong> \u2014 l\u2019immunit\u00e9 n\u2019\u00e9tant pas permanente, les adultes doivent recevoir une revaccination r\u00e9guli\u00e8re tous les 10 ans ;<\/li>\n\n\n\n<li><strong>contre certaines infections (par exemple, la coqueluche)<\/strong> \u2014 la revaccination est importante \u00e0 l\u2019adolescence et \u00e0 l\u2019\u00e2ge adulte, car l\u2019effet de la vaccination infantile dispara\u00eet apr\u00e8s 3 \u00e0 5 ans ;<\/li>\n\n\n\n<li><strong>pour la protection contre les virus sujets \u00e0 des mutations rapides (par exemple, le coronavirus)<\/strong> \u2014 des doses de rappel sont administr\u00e9es afin de maintenir la protection. Dans ce cas, la revaccination augmente non seulement le titre global d\u2019anticorps, mais \u00ab actualise \u00bb \u00e9galement la base de donn\u00e9es immunitaire en exposant l\u2019organisme \u00e0 de nouvelles souches de l\u2019agent pathog\u00e8ne.<\/li>\n<\/ul>\n\n<p class=\"wp-block-paragraph\"><\/p>\n","protected":false},"excerpt":{"rendered":"<p>La revaccination (du latin <em>re-<\/em> \u2014 renouvellement, r\u00e9p\u00e9tition et <em>vaccinus<\/em> \u2014 bovin) est l\u2019administration r\u00e9p\u00e9t\u00e9e d\u2019un antig\u00e8ne vaccinal \u00e0 une personne ayant d\u00e9j\u00e0 suivi un sch\u00e9ma complet de primovaccination.<\/p>\n","protected":false},"featured_media":0,"template":"","class_list":["post-8362","glossary_item","type-glossary_item","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v25.0 (Yoast SEO v27.8) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Revaccination 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